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Channel: Delirium – The Bottom Line
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HOPE-ICU

In critically ill patients does early treatment with haloperidol decrease the time that survivors spend in delirium or coma?

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Xian Su

In elderly patients following non-cardiac surgery, does a low dose dexmedetomidine infusion, compared with placebo, decrease the incidence of delirium?

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Simons

In adult ICU patients, does the use dynamic light therapy compared to normal lighting, reduce the incidence and duration of ICU-acquired delirium?

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DESIRE

In ventilated patients with sepsis, does a sedation strategy with dexmedetomidine compared with no dexmedetomidine improve mortality and number of ventilator-free days?

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MoDUS

In mechanically ventilated patients, does the early administration of simvastatin compared to placebo reduce the incidence of brain dysfunction (delirium and / or coma)?

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Skrobik

In delirium free critically ill adult patients receiving sedation, does the addition of nocturnal low dose dexmedetomidine prevent delirium and improve sleep?

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Nishikimi

In critically ill adults, does the administration of ramelteon compared to placebo reduce the length of intensive care stay?

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MIND-USA

In delirious adult ICU patients, does the administration of haloperidol or ziprasidone reduce the duration of delirium when compared with placebo?

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SPICE III

In ventilated, critically ill patients, does the use of dexmedetomidine as the primary sedative agent compared with usual sedative agents effect 90 day mortality?

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REDUCE Haloperidol

In critically ill adults, does haloperidol 1 mg or haloperidol 2 mg given three times a day compared to placebo reduce mortality?

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